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Title: Nocturnal awakening with headache and its relationship with sleep disorders in a population-based sample of adult inhabitants of São Paulo City, Brazil
Authors: Lucchesi, Ligia Mendonca [UNIFESP]
Speciali, Jose Geraldo
Santos-Silva, Rogerio [UNIFESP]
Taddei, Jose Augusto [UNIFESP]
Tufik, Sergio [UNIFESP]
Azeredo Bittencourt, Lia Rita [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Keywords: nocturnal awakening
sleep disorders
Issue Date: 1-Dec-2010
Publisher: Sage Publications Ltd
Citation: Cephalalgia. London: Sage Publications Ltd, v. 30, n. 12, p. 1477-1485, 2010.
Abstract: Our aim was to estimate the prevalence of nocturnal awakening with headache (NAH) in the population of São Paulo City according to gender, age (20-80 years old) and socioeconomic classes and its relationship to sleep disorders, sleep parameters, anxiety, depression, fatigue, life quality and obesity. We used a population-based survey with a representative three-stage cluster sample. Questionnaires and scales were applied face-to-face, and polysomnography was performed in 1101 volunteers, aged 42 +/- 14 years, 55% women. the complaint of NAH occurring at least once a week had a prevalence of 8.4%, mostly in women, obese subjects and those aged 50-59 years-old. We observed associations of NAH with insomnia, restless leg syndrome (RLS), nightmares and bruxism, but not obstructive sleep apnea syndrome. in a logistics regression model, risk factors for NAH were female gender, odds ratio (OR) (95% confidence interval [CI]) 4.5 (2.8-7.3); obesity, OR 1.9 (1.1-3.3); age between 50 and 59 years, OR 2.4 (1.2-4.7); severe anxiety, OR 8.1 (3.6-18.1); RLS, 2.7 (1.2-5.6); and nightmares, 2.2 (1.3-3.7). Our study shows that NAH was highly prevalent in the population of São Paulo and suggests that this phenomenon has specific characteristics with specific risk factors: obesity, RLS and nightmares.
ISSN: 0333-1024
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