Please use this identifier to cite or link to this item: https://repositorio.unifesp.br/handle/11600/32654
Title: Biomonitoring of DNA damage and cytotoxicity in individuals exposed to cone beam computed tomography
Authors: Carlin, Viviane [UNIFESP]
Artioli, A. J.
Matsumoto, M. A.
Filho, H. N.
Borgo, E.
Oshima, Celina Tizuko Fujiyama [UNIFESP]
Ribeiro, Daniel Araki [UNIFESP]
Universidade Federal de São Paulo (UNIFESP)
Sagrado Coracao Univ
Universidade de São Paulo (USP)
Keywords: buccal mucosa cells
cone beam computed tomography
micronucleus test
Issue Date: 1-Jul-2010
Publisher: British Inst Radiology
Citation: Dentomaxillofacial Radiology. London: British Inst Radiology, v. 39, n. 5, p. 295-299, 2010.
Abstract: Objectives: the aim of the present study was to evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis and karyorrhexis) in exfoliated buccal mucosa cells from adults following cone beam CT exposure.Methods: A total of 19 healthy adults (10 men and 9 women) submitted to cone beam CT were included.Results: No significant statistically differences (P > 0.05) in micronucleus frequency were seen before and after cone beam CT exposure. in contrast, the tomography was able to increase other nuclear alterations closely related to cytotoxicity such as karyorrhexis, pyknosis and karyolysis (P < 0.05).Conclusion: in summary, these data indicate that cone beam CT may not be a factor that induces chromosomal damage, but it is able to promote cytotoxicity. Dentomaxillofacial Radiology (2010) 39, 295-299. doi: 10.1259/dmfr/17573156
URI: http://repositorio.unifesp.br/handle/11600/32654
ISSN: 0250-832X
Other Identifiers: http://dx.doi.org/10.1259/dmfr/17573156
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