Reliability study of the Behavioral Assessment of the Dysexecutive Syndrome adapted for a Brazilian sample of older-adult controls and probable early Alzheimer's disease patients

Reliability study of the Behavioral Assessment of the Dysexecutive Syndrome adapted for a Brazilian sample of older-adult controls and probable early Alzheimer's disease patients

Alternative title Um estudo de confiabilidade da Bateria de Avaliação da Síndrome Disexecutiva adaptada para uma amostra brasileira de idosos controles e pacientes com doença de Alzheimer provável em fase inicial
Author Canali, Fabíola Autor UNIFESP Google Scholar
Brucki, Sonia Maria Dozzi Autor UNIFESP Google Scholar
Bertolucci, Paulo Henrique Ferreira Autor UNIFESP Google Scholar
Bueno, Orlando Francisco Amodeo Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Hospital Santa Marcelina
Abstract OBJECTIVE: Ecological tests are useful in assessing executive function deficits and may be of value in appraising response to treatment in Alzheimer's disease patients. Our aims were to examine executive function using the Behavioral Assessment of the Dysexecutive Syndrome for a Brazilian sample of older-adult controls and probable early Alzheimer's disease patients, and verify the applicability of this test battery. METHOD: Forty-one older-adult controls were matched with mild Alzheimer's disease patients by age, education, and gender. RESULTS: There significant inter-group differences in overall profile and almost all subtests except temporal judgment, time spent on planning the first and second Zoo Map visit, number of errors when copying drawings, naming pictures and Six Modified Elements arithmetic, and dysexecutive questionnaire self-rating. The Behavioral Assessment of the Dysexecutive Syndrome item that best discriminated controls from patients was the Modified Six Elements - adapted (general index), with a sensitivity of 80% and specificity of 90%, (AUC = 0.91, p < 0.001). CONCLUSION: Behavioral Assessment of the Dysexecutive Syndrome was effective in detecting executive function deficits in mild Alzheimer's disease patients, particularly the task switching, time monitoring, and rule-shift subtests.

OBJETIVO: Testes ecológicos são os mais indicados para a avaliação dos déficits nas funções executivas, sendo importante também na avaliação da resposta ao tratamento de pacientes com doença de Alzheimer. O objetivo deste estudo é verificar o desempenho nas funções executivas usando a Behavioural Assessment of the Dysexecutive Syndrome em uma amostra brasileira de idosos controles e pacientes com doença de Alzheimer provável em fase inicial e a aplicabilidade desta bateria ecológica em nosso meio. MÉTODO: Avaliamos com a Behavioural Assessment of the Dysexecutive Syndrome 41 idosos controles e 41 pacientes com doença de Alzheimer provável em fase inicial, sem diferença estatisticamente significativa em relação à idade, escolaridade e sexo. RESULTADOS: Houve diferença estatisticamente significativa entre os grupos no escore total e em quase todos os subtestes da Behavioural Assessment of the Dysexecutive Syndrome, não ocorrendo o mesmo no subteste de Julgamento Temporal, no tempo gasto no planejamento da primeira e segunda visita no Mapa do Zoológico, no número de erros ao copiar os desenhos, na nomeação de figuras e na aritmética do Seis Elementos Modificado e no questionário disexecutivo autoavaliação. CONCLUSÃO: A Behavioural Assessment of the Dysexecutive Syndrome mostrou-se eficaz na detecção dos déficits em funções executivas em pacientes com doença de Alzheimer provável em fase inicial, particularmente em tarefas de alternância, monitoramento de tempo e subtestes de mudanças de regras.
Keywords Alzheimer's disease
Executive functions
Dementia
Signs and symptoms
Neuropsychological tests
Doença de Alzheimer
Funções executivas
Demência
Sinais e sintomas
Testes neuropsicológicos
Language English
Date 2011-12-01
Published in CANALI, Fabíola et al . Reliability study of the Behavioral Assessment of the Dysexecutive Syndrome adapted for a Brazilian sample of older-adult controls and probable early Alzheimer's disease patients. Rev. Bras. Psiquiatr., São Paulo , v. 33, n. 4, p. 338-346, dez. 2011
ISSN 1516-4446 (Sherpa/Romeo, impact factor)
Publisher Associação Brasileira de Psiquiatria - ABP
Extent 338-346
Origin http://dx.doi.org/10.1590/S1516-44462011005000015
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000298331500006
SciELO ID S1516-44462011000400006 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/6711

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