Impact of oxygen supply on surfactin biosynthesis using brewery waste as substrate

Impact of oxygen supply on surfactin biosynthesis using brewery waste as substrate

Título alternativo Impact of oxygen supply on surfactin biosynthesis using brewery waste as substrate
Autor Zanutto, Talita Corrêa Nazareth Google Scholar
Zanutto, Conrado Planas Google Scholar
Maass, Danielle Autor UNIFESP Google Scholar
Souza, Antônio Augusto Ulson de Google Scholar
Souza, Selene Maria de Arruda Guelli Ulson de Google Scholar
Resumo This work reports surfactin production by B. subtilis ATCC 6051 in a stirred tank bioreactor, where trub was used as a carbon source. Trub is a residue from the brewing industry mainly composed of high-molar-mass proteins and reducing sugars, being a sustainable and low-cost substrate for bioprocess. Despite this, Trub has been little explored as a raw material in bioprocesses. Aiming to evaluate important factors in scale-up process, the impact of oxygen transfer coefficient (KLa) concerning volumetric productivity, and the effect of agitation (150–300 rpm) and aeration (0.5–1.5 vvm) on biosurfactant production by a Full Factorial design were evaluated. Only agitation presented a significant effect on surfactin concentration (SF), where SF was described by a linear regression model (R2 = 0.99). The biosurfactant showed high stability in relation to variations in temperature and pH. In addition, the foam collecting was an efficient method in recovering and enrichment of the product.
Assunto Biosurfactant
Surfactin
Brewery waste
Bioreactor
Volumetric oxygen mass transfer coefficient
Cobertura Amsterdam
Idioma Inglês
Financiador Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Número do financiamento #2019/07659-4
Data 2021-03-15
ISSN 2213-3437 (Sherpa/Romeo)
Editor Elsevier
Fonte https://www.sciencedirect.com/science/article/pii/S2213343721003493
Direito de acesso Acesso restrito
Tipo Artigo
URI https://repositorio.unifesp.br/handle/11600/60836

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