Plasma Leptin and Premenstrual Syndrome: A Review

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dc.contributor.author Martinho Nicolau, Zaira Fernanda [UNIFESP]
dc.contributor.author Bezerra, Andreia Gomes [UNIFESP]
dc.contributor.author Polesel, Daniel Ninello [UNIFESP]
dc.contributor.author Andersen, Monica Levy [UNIFESP]
dc.contributor.author Tufik, Sergio [UNIFESP]
dc.contributor.author Hachul, Helena [UNIFESP]
dc.date.accessioned 2020-09-01T13:21:26Z
dc.date.available 2020-09-01T13:21:26Z
dc.date.issued 2017
dc.identifier http://dx.doi.org/10.1097/OGX.0000000000000502
dc.identifier.citation Obstetrical & Gynecological Survey. Philadelphia, v. 72, n. 11, p. 659-662, 2017.
dc.identifier.issn 0029-7828
dc.identifier.uri https://repositorio.unifesp.br/handle/11600/58262
dc.description.abstract Importance Premenstrual syndrome (PMS) is characterized by physical and psychological symptoms in the luteal phase. Leptin can influence PMS as it acts on the hypothalamic-pituitary-gonadal axis. Objective The aim of this study was to evaluate data in the literature about the profile of plasma leptin in women with PMS. Evidence Acquisition We performed a search of databases using both descriptors. Three studies were identified. They included 181 participants. Two of these studies found higher leptin levels in women with PMS. Results Conflicting results were found regarding the leptin levels in the luteal phase and the correlation between leptin, estradiol, and progesterone levels. Conclusions and Relevance Leptin could have a role in the pathophysiology of PMS and indicate degree of severity of PMS. Future studies on the role of leptin in PMS are needed. Target Audience Obstetricians and gynecologists, family physicians. Learning Objectives After completing this activity, the learner should be better able to describe the correlation between women with PMS and leptin concentration, analyze if there is a difference between leptin concentration in the phases of the menstrual cycle, and foresee the future clinical applicability of leptin's concentration in women with PMS. en
dc.format.extent 659-662
dc.language.iso eng
dc.publisher Lippincott Williams & Wilkins
dc.relation.ispartof Obstetrical & Gynecological Survey
dc.rights Acesso restrito
dc.title Plasma Leptin and Premenstrual Syndrome: A Review en
dc.type Artigo
dc.description.affiliation Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo, Brazil
dc.description.affiliation Univ Fed Sao Paulo, Head Womens Sleep Med Div, Dept Psychobiol, Sao Paulo, Brazil
dc.description.affiliation Univ Fed Sao Paulo, Head Womens Sleep Med Div, Dept Gynecol, Sao Paulo, Brazil
dc.description.affiliation Casa Saude Santa Marcelina, Dept Gynecol, Sao Paulo, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Head Womens Sleep Med Div, Dept Psychobiol, Sao Paulo, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo, Head Womens Sleep Med Div, Dept Gynecol, Sao Paulo, Brazil
dc.identifier.doi 10.1097/OGX.0000000000000502
dc.description.source Web of Science
dc.identifier.wos WOS:000416005500018
dc.coverage Philadelphia
dc.citation.volume 72
dc.citation.issue 11



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