Physical exercise, neuroplasticity, spatial learning and memory

Physical exercise, neuroplasticity, spatial learning and memory

Author Cassilhas, Ricardo C. Autor UNIFESP Google Scholar
Tufik, Sergio Autor UNIFESP Google Scholar
de Mello, Marco Tulio Google Scholar
Abstract There has long been discussion regarding the positive effects of physical exercise on brain activity. However, physical exercise has only recently begun to receive the attention of the scientific community, with major interest in its effects on the cognitive functions, spatial learning and memory, as a non-drug method of maintaining brain health and treating neurodegenerative and/or psychiatric conditions. In humans, several studies have shown the beneficial effects of aerobic and resistance exercises in adult and geriatric populations. More recently, studies employing animal models have attempted to elucidate the mechanisms underlying neuroplasticity related to physical exercise-induced spatial learning and memory improvement, even under neurodegenerative conditions. In an attempt to clarify these issues, the present review aims to discuss the role of physical exercise in the improvement of spatial learning and memory and the cellular and molecular mechanisms involved in neuroplasticity.
Keywords Aerobic exercise
Resistance exercise
xmlui.dri2xhtml.METS-1.0.item-coverage Basel
Language English
Sponsor Sao Paulo Research Foundation (FAPESP)
Department of Physical Education - Universidade Federal dos Vales do Jequit-inhonha e Mucuri (UVFJM)
School of Physical Education, Physiotherapy and Occupational Therapy (EEFFTO) - Universidade Federal de Minas Gerais (UFMG)
Department of Psychobiology Universidade Federal de Sao Paulo (UNIFESP)
National Council for Scientific and Technological Development (CNPq)
Grant number FAPESP: 2013/05018-5
CNPq: 478229/2013-5
Date 2016
Published in Cellular And Molecular Life Sciences. Basel, v. 73, n. 5, p. 975-983, 2016.
ISSN 1420-682X (Sherpa/Romeo, impact factor)
Publisher Springer Basel Ag
Extent 975-983
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000369535000005

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