Activation of C-fiber nociceptors by low-power diode laser

Activation of C-fiber nociceptors by low-power diode laser

Author Azevedo, Eduardo Autor UNIFESP Google Scholar
Silva, Andressa Autor UNIFESP Google Scholar
Martins, Raquel Autor UNIFESP Google Scholar
Andersen, Monica L. Autor UNIFESP Google Scholar
Tufik, Sergio Autor UNIFESP Google Scholar
Manzano, Gilberto M. Autor UNIFESP Google Scholar
Abstract Objective: The evaluation of selective activation of C-fibers to record evoked potentials using the association of low-power diode laser (810 nm), tiny-area stimulation and skin-blackening. Method: Laser-evoked potentials (LEPs) were obtained from 20 healthy young subjects. An aluminum plate with one thin hole was attached to the laser probe to provide tiny-area stimulation of the hand dorsum and the stimulated area was covered with black ink. Results: The mean intensity used for eliciting the ultra-late laser-evoked potential (ULEP) was 70 +/- 32 mW. All subjects showed a clear biphasic potential that comprised a negative peak (806 +/- 61 ms) and a positive deflection (1033 +/- 60 ms), corresponding to the ULEP related to C-fiber activation. Conclusion: C-fiber-evoked responses can be obtained using a very low-power diode laser when stimulation is applied to tiny areas of darkened skin. This strategy offers a non-invasive and easy methodology that minimizes damage to the tissue.
Keywords laser-evoked potentials
pain perception
xmlui.dri2xhtml.METS-1.0.item-coverage Sao Paulo Sp
Language English
Date 2016
Published in Arquivos De Neuro-Psiquiatria. Sao Paulo Sp, v. 74, n. 3, p. 223-227, 2016.
ISSN 0004-282X (Sherpa/Romeo, impact factor)
Publisher Assoc Arquivos Neuro- Psiquiatria
Extent 223-227
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000374191900009
SciELO ID S0004-282X2016000300009 (statistics in SciELO)

Show full item record


Name: S0004-282X2016000300009-en.pdf
Size: 386.5Kb
Format: PDF
Open file

This item appears in the following Collection(s)




My Account