What do Cochrane systematic reviews say about interventions for vitamin D supplementation?

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dc.contributor.author Mateussi, Mariana Vendramin [UNIFESP]
dc.contributor.author Cruz Latorraca, Carolina de Oliveira [UNIFESP]
dc.contributor.author Daou, Julia Pozetti [UNIFESP]
dc.contributor.author Cabrera Martimbianco, Ana Luiza [UNIFESP]
dc.contributor.author Riera, Rachel [UNIFESP]
dc.contributor.author Pacheco, Rafael Leite [UNIFESP]
dc.contributor.author Pachito, Daniela Vianna [UNIFESP]
dc.date.accessioned 2020-08-04T13:40:15Z
dc.date.available 2020-08-04T13:40:15Z
dc.date.issued 2017
dc.identifier http://dx.doi.org/10.1590/1516-3180.2017.0230150817
dc.identifier.citation Sao Paulo Medical Journal. Sao Paulo, v. 135, n. 5, p. 497-507, 2017.
dc.identifier.issn 1516-3180
dc.identifier.uri https://repositorio.unifesp.br/handle/11600/57397
dc.description.abstract CONTEXT AND OBJECTIVE: Despite the high prevalence of vitamin D supplementation, its use remains controversial. The objective of this review was to identify and summarize the evidence from Cochrane systematic reviews regarding vitamin D supplementation for preventing or treating any clinical condition. DESIGN AND SETTING: Review of systematic reviews, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de Sao Paulo. METHODS: A search was conducted to identify all Cochrane systematic reviews that fulfilled the inclusion criteria. Titles and abstracts were screened by two authors. RESULTS: We included 27 Cochrane systematic reviews: 10 assessing use of vitamin D for prevention and 17 for treatment. The reviews found moderate to high quality of evidence regarding the benefit of vitamin D for pregnant women (prevention of adverse events: preterm birth risk [rate ratio, RR 0.36 en
dc.description.abstract 95% confidence interval, CI 0.14 to 0.93] and low birthweight risk [RR 0.40 en
dc.description.abstract 95% CI 0.24 to 0.67]) and for asthma patients (reduction of severe exacerbations [RR 0.63 en
dc.description.abstract 95% CI 0.45 to 0.88]). No benefit was found regarding vitamin D supplementation alone (without calcium) for preventing hip or any new fracture. For all other outcomes assessed under various conditions, the current quality of evidence is low or unknown, and therefore insufficient for any recommendation. CONCLUSION: Based on moderate to high quality of evidence, the Cochrane systematic reviews included here showed that there were some benefits from vitamin D supplementation for pregnant women and asthma patients and no benefits for preventing fractures. en
dc.format.extent 497-507
dc.language.iso eng
dc.publisher Associacao Paulista Medicina
dc.relation.ispartof Sao Paulo Medical Journal
dc.rights Acesso aberto
dc.subject Review en
dc.subject Vitamin D en
dc.subject Evidence-based medicine en
dc.subject Evaluation of results of therapeutic interventions en
dc.subject Evidence-based practice en
dc.title What do Cochrane systematic reviews say about interventions for vitamin D supplementation? en
dc.type Artigo
dc.description.affiliation Univ Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Discipline Evidence Based Hlth, Sao Paulo, SP, Brazil
dc.description.affiliation Univ Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliation Univ Fed Sao Paulo Unifesp, Postgrad Evidence Based Hlth Program, Sao Paulo, SP, Brazil
dc.description.affiliation Cochrane Brazil, Sao Paulo, SP, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Discipline Evidence Based Hlth, Sao Paulo, SP, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo EPM Unifesp, Escola Paulista Med, Sao Paulo, SP, Brazil
dc.description.affiliationUnifesp Univ Fed Sao Paulo Unifesp, Postgrad Evidence Based Hlth Program, Sao Paulo, SP, Brazil
dc.identifier.file S1516-31802017000500497.pdf
dc.identifier.scielo S1516-31802017000500497
dc.identifier.doi 10.1590/1516-3180.2017.0230150817
dc.description.source Web of Science
dc.identifier.wos WOS:000417223700014
dc.coverage Sao Paulo
dc.citation.volume 135
dc.citation.issue 5



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