Risk factors for advanced resuscitation in term and near-term infants: a case-control study

Risk factors for advanced resuscitation in term and near-term infants: a case-control study

Author Pablo Berazategui, Juan Google Scholar
Aguilar, Adriana Google Scholar
Escobedo, Marilyn Google Scholar
Dannaway, Douglas Google Scholar
Guinsburg, Ruth Autor UNIFESP Google Scholar
Almeida, Maria Fernanda Branco de Autor UNIFESP Google Scholar
Saker, Firas Google Scholar
Fernandez, Ariel Google Scholar
Albornoz, Guadalupe Google Scholar
Valera, Mariana Google Scholar
Amado, Daniel Google Scholar
Puig, Gabriela Google Scholar
Althabe, Fernando Google Scholar
Szyld, Edgardo Google Scholar
Abstract Objective (1) To determine which antepartum and/or intrapartum factors are associated with the need for advanced neonatal resuscitation (ANR) at birth in infants with gestational age (GA) >= 34 weeks. (2) To develop a risk score for the need for ANR in neonates with GA >= 34 weeks. Design Prospective multicentre, case control study. In total, 16 centres participated in this study: 10 in Argentina, 1 in Chile, 3 in Brazil and 2 in the USA. Results A case control study conducted from December 2011 to April 2013. Of a total of 61 593 births, 58 429 were reported as an GA >= 34 weeks, and of these, only 219 (0.37%) received ANR. After excluding 23 cases, 196 cases and 784 consecutive birth controls were included in the analysis. The final model was generated with three antepartum and seven intrapartum factors, which correctly classified 88.9% of the observations. The area under the receiver operating characteristic (AROC) performed to evaluate discrimination was 0.88, 95% CI 0.62 to 0.91. The AROC performed for external validity testing of the model in the validation sample was 0.87 with 95% CI 0.58 to 0.92. Conclusions We identified 10 risk factors significantly associated with the need for ANR in newborns >= 34 weeks. We developed a validated risk score that allows the identification of newborns at higher risk of need for ANR. Using this tool, the presence of specialised personnel in the delivery room may be designated more appropriately.
xmlui.dri2xhtml.METS-1.0.item-coverage London
Language English
Sponsor FUNDASAMIN (Fundacion para la Salud Materno Infantil)
IECS (Institute de Efectividad Clinica y Sanitaria), Buenos Aires, Argentina
Date 2017
Published in Archives Of Disease In Childhood-Fetal And Neonatal Edition. London, v. 102, n. 1, p. F44-F50, 2017.
ISSN 1359-2998 (Sherpa/Romeo, impact factor)
Publisher Bmj Publishing Group
Extent F44-F50
Origin http://dx.doi.org/10.1136/archdischild-2015-309525
Access rights Closed access
Type Article
Web of Science ID WOS:000391899100010
URI https://repositorio.unifesp.br/handle/11600/56498

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