Second-generation central venous catheter in the prevention of bloodstream infection: a systematic review

Second-generation central venous catheter in the prevention of bloodstream infection: a systematic review

Autor Dorociaki Stocco, Janislei Gislei Google Scholar
Hoers, Hellen Google Scholar
Pott, Franciele Soares Google Scholar
Crozeta, Karla Google Scholar
Barbosa, Dulce Aparecida Autor UNIFESP Google Scholar
Meier, Marineli Joaquim Google Scholar
Resumo Objective: to evaluate the effectiveness and safety in the use of second-generation central venous catheters impregnated in clorhexidine and silver sulfadiazine when compared with other catheters, being them impregnated or not, in order to prevent the bloodstream infection prevention. Method: systematic review with meta-analysis. Databases searched: MEDLINE, EMBASE, CINAHL, LILACS/SciELO, Cochrane CENTRAL

search in Congress Proceedings and records from Clinical Trials. Results: 1.235 studies were identified, 97 were pre-selected and 4 were included. In catheter-related bloodstream infection, there was no statistical significance between second-generation impregnated catheter compared with the non-impregnated ones, absolute relative risk 1,5% confidence interval 95% (3%-1%), relative risk 0,68 (confidence interval 95%, 0,40-1,15) and number needed to treat 66. In the sensitivity analysis, there was less bloodstream infection in impregnated catheters (relative risk 0,50, confidence interval 95%, 0,26-0,96). Lower colonization, absolute relative risk 9,6% (confidence interval 95%, 10% to 4%), relative risk 0,51 (confidence interval 95% from 0,38-0,85) and number needed to treat 5. Conclusion: the use of second-generation catheters was effective in reducing the catheter colonization and infection when a sensitivity analysis is performed. Future clinical trials are suggested to evaluate sepsis rates, mortality and adverse effects.
Assunto Catheterization, Central Venous
Catheter-Related Infection
Colonization
Sepsis
Meta-AnalysisSilver-Sulfadiazine
Controlled-Trial
Chlorhexidine
Guidelines
Hospitals
Idioma Inglês
Data 2016
Publicado em Revista Latino-Americana De Enfermagem. Ribeirao preto, v. 24, p. e2722, 2016.
ISSN 1518-8345 (Sherpa/Romeo, fator de impacto)
Editor Soc Brasil Pediatria
Extensão e2722
Fonte http://dx.doi.org/10.1590/1518-8345.0756.2722
Direito de acesso Acesso aberto Open Access
Tipo Artigo
Web of Science WOS:000380887900028
SciELO S0104-11692016000100605 (estatísticas na SciELO)
URI http://repositorio.unifesp.br/handle/11600/49428

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