Predictive factors of overall quality of life in advanced cancer patients using EORTC QLQ-C30

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dc.contributor.author Cramarossa, Gemma
dc.contributor.author Zeng, Liang
dc.contributor.author Zhang, Liying
dc.contributor.author Tseng, Ling-Ming
dc.contributor.author Hou, Ming-Feng
dc.contributor.author Fairchild, Alysa
dc.contributor.author Vassiliou, Vassilios
dc.contributor.author Jesus-Garcia, Reynaldo [UNIFESP]
dc.contributor.author El-Din, Mohamed A. Alm
dc.contributor.author Kumar, Aswin
dc.contributor.author Forges, Fabien
dc.contributor.author Chie, Wei-Chu
dc.contributor.author Sahgal, Arjun
dc.contributor.author Lam, Henry
dc.contributor.author Pulenzas, Natalie
dc.contributor.author Chow, Edward
dc.date.accessioned 2016-01-24T14:35:17Z
dc.date.available 2016-01-24T14:35:17Z
dc.date.issued 2014-02-01
dc.identifier http://dx.doi.org/10.1586/14737167.2014.864560
dc.identifier.citation Expert Review of Pharmacoeconomics & Outcomes Research. London: Expert Reviews, v. 14, n. 1, p. 139-146, 2014.
dc.identifier.issn 1473-7167
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/37420
dc.description.abstract Objective: To identify which domains/symptoms from the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) were predictive of overall quality of life (QoL) in advanced cancer patients. Methods: Four hundred and forty seven patients with brain metastases or bone metastases from seven countries were enrolled with regression analysis to determine the predictive value of the QLQ-C30 functional/symptom scores for patient reported overall QoL (question 30), overall health (question 29) and the global health status domain (questions 29 and 30). Results: Worse role functioning, social functioning, fatigue and financial problems were the most significant predictive factors for worse QoL. in the bone metastases subgroup (n = 400), role functioning, fatigue and financial problems were the most significant predictors. in patients with brain metastases (n = 47), none of the EORTC domains significantly predicted worse QOL. Conclusion: Deterioration of certain QLQ-C30 functional/symptom scores significantly contributes to worse QoL, overall health and global health status. en
dc.description.sponsorship Bratty Family Fund
dc.description.sponsorship Michael and Karyn Goldstein Cancer Research Fund
dc.description.sponsorship Joseph and Silvana Melara Cancer Research Fund
dc.description.sponsorship Ofelia Cancer Research Fund
dc.format.extent 139-146
dc.language.iso eng
dc.publisher Expert Reviews
dc.relation.ispartof Expert Review of Pharmacoeconomics & Outcomes Research
dc.rights Acesso restrito
dc.subject advanced cancer en
dc.subject EORTC QLQ-C30 en
dc.subject metastatic cancer en
dc.subject quality of life en
dc.subject symptom control en
dc.title Predictive factors of overall quality of life in advanced cancer patients using EORTC QLQ-C30 en
dc.type Artigo
dc.contributor.institution Univ Toronto
dc.contributor.institution Natl Yang Ming Univ
dc.contributor.institution Kaohsiung Med Univ Hosp
dc.contributor.institution Cross Canc Inst
dc.contributor.institution Bank Cyprus
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Tanta Univ Hosp
dc.contributor.institution Reg Canc Ctr
dc.contributor.institution St Etienne Univ Hosp
dc.contributor.institution Natl Taiwan Univ
dc.description.affiliation Univ Toronto, Sunnybrook Hlth Sci Ctr, Dept Radiat Oncol, Odette Canc Ctr, Toronto, ON M4N 3M5, Canada
dc.description.affiliation Natl Yang Ming Univ, Taipei Vet Gen Hosp, Dept Surg, Taipei 112, Taiwan
dc.description.affiliation Kaohsiung Med Univ Hosp, Dept Surg Gastroenterol, Kaohsiung, Taiwan
dc.description.affiliation Cross Canc Inst, Dept Radiat Oncol, Edmonton, AB T6G 1Z2, Canada
dc.description.affiliation Bank Cyprus, Dept Radiat Oncol, Ctr Oncol, Nicosia, Cyprus
dc.description.affiliation Universidade Federal de São Paulo, Dept Orthoped Oncol, São Paulo, Brazil
dc.description.affiliation Tanta Univ Hosp, Tanta Fac Med, Dept Clin Oncol, Tanta, Egypt
dc.description.affiliation Reg Canc Ctr, Div Gynaecol & Genitourinary Oncol, Dept Radiat Oncol, Trivandrum 695011, Kerala, India
dc.description.affiliation St Etienne Univ Hosp, INSERM, CIE3, St Etienne, France
dc.description.affiliation St Etienne Univ Hosp, Unit Clin Res Innovat & Pharmacol, St Etienne, France
dc.description.affiliation Natl Taiwan Univ, Dept Publ Hlth, Taipei 10764, Taiwan
dc.description.affiliation Natl Taiwan Univ, Inst Epidemiol & Preventat Med, Taipei 10764, Taiwan
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Orthoped Oncol, São Paulo, Brazil
dc.identifier.doi 10.1586/14737167.2014.864560
dc.description.source Web of Science
dc.identifier.wos WOS:000336258600015



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