Incidence and Main Risk Factors for Severe Retinopathy of Prematurity in Infants Weighing Less Than 1000 Grams in Brazil

Incidence and Main Risk Factors for Severe Retinopathy of Prematurity in Infants Weighing Less Than 1000 Grams in Brazil

Author Fortes Filho, Joao Borges Google Scholar
Borges Fortes, Barbara Gastal Google Scholar
Tartarella, Marcia Beatriz Autor UNIFESP Google Scholar
Procianoy, Renato Soibelmann Google Scholar
Institution Univ Fed Rio Grande do Sul
Universidade Federal de São Paulo (UNIFESP)
Abstract Objectives: This study evaluated the incidence and risk factors for severe retinopathy of prematurity (ROP) in babies <1000 g at Porto Alegre, Brazil.Methods: Prospective cohort study including premature children with birth weight <= 1000 g was conducted. Main outcome was the occurrence of severe ROP needing treatment.Results: A total of 157 infants were included. Severe ROP occurred in 20 infants (12.7%). Nineteen patients were treated by laser photocoagulation. Main risk factors for severe ROP were gestational age (P=0.029), infant's weight measured at sixth week of life (P<0.001) and number of days of oxygen therapy under mechanical ventilation (P<0.001). After logistic regression, infant's weight at sixth week of life and number of days in mechanical ventilation were associated to severe ROP.Conclusions: We reported the incidence of 12.7% of severe ROP among babies born <= 1000 g in our institution. Laser photocoagulation was effective to stabilize the disease among 19 treated patients.
Keywords prematurity
retinopathy of prematurity
incidence
risk factors
blindness
prevention
Language English
Date 2013-12-01
Published in Journal of Tropical Pediatrics. Oxford: Oxford Univ Press, v. 59, n. 6, p. 502-506, 2013.
ISSN 0142-6338 (Sherpa/Romeo, impact factor)
Publisher Oxford Univ Press
Extent 502-506
Origin http://dx.doi.org/10.1093/tropej/fmt036
Access rights Closed access
Type Article
Web of Science ID WOS:000328055600013
URI http://repositorio.unifesp.br/handle/11600/37057

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