Analysis of Transmitted Resistance to Raltegravir and Selective Pressure among HIV-1-Infected Patients on a Failing HAART in São Paulo, Brazil

Mantovani, N. P.; Azevedo, R. G.; Rabelato, J. T.; Sanabani, S.; Diaz, R. S.; Komninakis, S. V.

doi:10.1128/JCM.00539-12

dc.contributor.author	Mantovani, N. P. [UNIFESP]
dc.contributor.author	Azevedo, R. G. [UNIFESP]
dc.contributor.author	Rabelato, J. T.
dc.contributor.author	Sanabani, S.
dc.contributor.author	Diaz, R. S. [UNIFESP]
dc.contributor.author	Komninakis, S. V. [UNIFESP]
dc.date.accessioned	2016-01-24T14:27:17Z
dc.date.available	2016-01-24T14:27:17Z
dc.date.issued	2012-06-01
dc.identifier	http://dx.doi.org/10.1128/JCM.00539-12
dc.identifier.citation	Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 50, n. 6, p. 2122-2125, 2012.
dc.identifier.issn	0095-1137
dc.identifier.uri	http://repositorio.unifesp.br/handle/11600/34920
dc.description.abstract	We studied the presence of primary resistance to raltegravir (RAL), natural polymorphisms, and selection pressure on HIV-1 integrase. We found a high frequency of integrase polymorphisms related to the resistance to RAL and sequence stability. Further studies are needed to determine the importance of these polymorphisms to RAL resistance.	en
dc.description.sponsorship	Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent	2122-2125
dc.language.iso	eng
dc.publisher	Amer Soc Microbiology
dc.relation.ispartof	Journal of Clinical Microbiology
dc.rights	Acesso aberto
dc.title	Analysis of Transmitted Resistance to Raltegravir and Selective Pressure among HIV-1-Infected Patients on a Failing HAART in São Paulo, Brazil	en
dc.type	Artigo
dc.contributor.institution	Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution	Lusiada Fdn Santos
dc.contributor.institution	Universidade de São Paulo (USP)
dc.description.affiliation	Fed Univ São Paulo UNIFESP, Div Infect Dis, Retrovirol Lab, São Paulo, Brazil
dc.description.affiliation	Lusiada Fdn Santos, Mol Biol Lab, Dept Med, Santos, Brazil
dc.description.affiliation	Univ São Paulo, Div Clin Immunol & Allergy, São Paulo, Brazil
dc.description.affiliationUnifesp	Fed Univ São Paulo UNIFESP, Div Infect Dis, Retrovirol Lab, São Paulo, Brazil
dc.description.sponsorshipID	FAPESP: 09/05712-3
dc.identifier.file	WOS000305119000056.pdf
dc.identifier.doi	10.1128/JCM.00539-12
dc.description.source	Web of Science
dc.identifier.wos	WOS:000305119000056