Assessment of aerobic capacity during swimming exercise in ob/ob mice

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dc.contributor.author Almeida, W. S.
dc.contributor.author Lima, L. C. J.
dc.contributor.author Cunha, V. N. C.
dc.contributor.author Cunha, R. R.
dc.contributor.author Araujo, R. C.
dc.contributor.author Barros, C. C. [UNIFESP]
dc.contributor.author Simoes, H. G.
dc.contributor.author Campbell, C. S. G.
dc.date.accessioned 2016-01-24T14:17:29Z
dc.date.available 2016-01-24T14:17:29Z
dc.date.issued 2011-12-01
dc.identifier http://dx.doi.org/10.1002/cbf.1803
dc.identifier.citation Cell Biochemistry and Function. Malden: Wiley-Blackwell, v. 29, n. 8, p. 666-672, 2011.
dc.identifier.issn 0263-6484
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/34265
dc.description.abstract Obesity is a highly prevalent condition associated with several diseases. Physical exercise has been considered as a non-pharmacological tool in the treatment of obesity. However, several aspects underlying exercise evaluation and prescription in obesity and associated pathologies are still under investigation. Although many research involving exercise have been performed in animal models, there is a lack of protocols for aerobic capacity assessment in obese animals, such as the ob/ob mice. This study aimed the following: (i) to verify the possibility of determining the lactate threshold (LT) on swimming exercise in ob/ob mice and in non-obese heterozygote mice (ob/OB), through visual inspection (vLT) and polynomial adjustment (pLT); and (ii) to verify if the LT determined through these protocols corresponds to the maximal lactate steady state (MLSS). Eight ob/ob and ten ob/OB mice performed an incremental exercise test to determine vLT and pLT as well as constant-load exercise bouts to determine MLSS. There were no within-group differences between vLT, pLT and MLSS [ob/ob: similar to 5.3% body weight (BW); ob/OB: similar to 3 center dot 6%BW] with a high agreement among protocols. in conclusion, the identification of the LT and MLSS intensities was possible for both groups. These data suggest that the proposed protocols may be used in new research on the effects of different exercise intensities on some aspects of obesity. Copyright (c) 2011 John Wiley & Sons, Ltd. en
dc.description.sponsorship Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent 666-672
dc.language.iso eng
dc.publisher Wiley-Blackwell
dc.relation.ispartof Cell Biochemistry and Function
dc.rights Acesso restrito
dc.subject aerobic exercise en
dc.subject lactate threshold en
dc.subject leptin en
dc.subject maximal lactate steady state en
dc.subject mice en
dc.title Assessment of aerobic capacity during swimming exercise in ob/ob mice en
dc.type Artigo
dc.rights.license http://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.contributor.institution Univ Catolica Brasilia
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Univ Catolica Brasilia, Programa Mestrado & Doutorado Educ Fis, BR-71966900 Taguatinga, DF, Brazil
dc.description.affiliation Univ Catolica Brasilia, Univ Brasilia UNB, Programa Mestrado Educ Fis, BR-71966900 Taguatinga, DF, Brazil
dc.description.affiliation Universidade Federal de São Paulo UNIFESP, Dept Med, Div Nefrol, São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo UNIFESP, Dept Biofis, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo UNIFESP, Dept Med, Div Nefrol, São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo UNIFESP, Dept Biofis, São Paulo, Brazil
dc.description.sponsorshipID CAPES: 0216054
dc.identifier.doi 10.1002/cbf.1803
dc.description.source Web of Science
dc.identifier.wos WOS:000297632400007



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