Recurrent Primary Acquired Melanosis With Atypia Involving a Clear Corneal Phacoemulsification Wound

Recurrent Primary Acquired Melanosis With Atypia Involving a Clear Corneal Phacoemulsification Wound

Author Colby, Kathryn Google Scholar
Bhat, Pooja Google Scholar
Novais, Gustavo Autor UNIFESP Google Scholar
Jakobiec, Frederick A. Google Scholar
Institution Harvard Univ
Universidade Federal de São Paulo (UNIFESP)
Abstract Purpose: To report a case of corneal primary acquired melanosis (PAM) with atypia after cataract surgery.Methods: Retrospective case report with literature review.Results: Excision of an elevated pigmented conjunctival lesion was performed at the time of cataract extraction by clear corneal phacoemulsification by an outside surgeon. Histopathologic examination revealed PAM with atypia. Three months after the initial surgery, recurrent melanosis involving the peripheral corneal epithelium was noted, with extension of pigment into the corneal stroma through the paracentesis site. Excision of the involved corneal epithelium and the adjacent conjunctiva was performed, and microscopically recurrent PAM with atypia was confirmed. Adjuvant cryotherapy was applied at the time of surgery, and topical mitomycin C was given postoperatively. Repeat biopsies revealed no remaining malignancy, and the intrastromal pigment has disappeared during 18 months of follow-up.Conclusion: We present this case to illustrate the importance of complete evaluation and treatment of potentially atypical melanocytic conjunctival lesions before proceeding with elective intraocular surgery.
Keywords primary acquired melanosis (PAM) with atypia
Bowman layer
corneal incision
conjunctival melanoma
cataract surgery
Language English
Date 2011-01-01
Published in Cornea. Philadelphia: Lippincott Williams & Wilkins, v. 30, n. 1, p. 114-116, 2011.
ISSN 0277-3740 (Sherpa/Romeo, impact factor)
Publisher Lippincott Williams & Wilkins
Extent 114-116
Access rights Closed access
Type Article
Web of Science ID WOS:000285086400023

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