Standard full-field electroretinography in healthy preterm infants

Standard full-field electroretinography in healthy preterm infants

Author Berezovsky, Adriana Autor UNIFESP Google Scholar
Moraes, NSB Google Scholar
Nusinowitz, S. Google Scholar
Salomão, Solange Rios Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Jules Stein Eye Inst
Abstract The purpose of this study was to determine electroretinographic parameters according to the standard protocol from the International Society for Clinical Electrophysiology of Vision (ISCEV) in healthy preterm infants with normal fundus. Seventeen healthy preterm infants with normal fundus were recruited and divided in two age groups: 3-week group, nine infants with mean adjusted age at test = 2.67 +/- 0.92 weeks and 8-week group, eight infants with mean adjusted age at test = 7.92 +/- 1.72 weeks. Full-field ERGs were obtained with a Burian-Allen bipolar contact lens electrode from the anesthetized cornea in one eye, through a fully dilated pupil after 30 min of dark adaptation. the standard ISCEV protocol was used and the following responses were recorded: rod, maximal, oscillatory potentials, cone and 30 Hz flicker. Median values and 1st, 5th, 95th and 99th percentiles for amplitude and implicit time are described for both age groups. There was statistically larger amplitude for 30 Hz flicker (t = 2.191; p = 0.046) and for cone response (t = 2.307; p = 0.044) in the 8-week-old group. Statistically shorter implicit times were found in 8-week group for rod response (t = 3.219; p = 0.015), cone response (t = 2.839; p = 0.016) and flicker response (t = 3.326; p = 0.005). Shortening of implicit time was evident in the older group of preterms and this finding is consistent with other maturational studies confirming the anatomical and functional development of the photoreceptors. Medians and ranges between the 1st and 99th and the 5th and 95th percentiles can be used as a baseline for future comparisons with infants with ROP.
Keywords electroretinography
retinal development
Language English
Date 2003-11-01
Published in Documenta Ophthalmologica. Dordrecht: Kluwer Academic Publ, v. 107, n. 3, p. 243-249, 2003.
ISSN 0012-4486 (Sherpa/Romeo, impact factor)
Publisher Kluwer Academic Publ
Extent 243-249
Access rights Closed access
Type Article
Web of Science ID WOS:000187637700005

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